Motor diary · 19 October 2026
19 October 2026: A Day on the Old Schedule
This was my father's schedule before the change. Some doses gave fairly predictable relief, but the 4 PM dose often did not help. Many doses failed to bring the relief we expected.
By an anonymous caregiver · 2 min read
Personal experience, not medical advice. I share our family's experience here. Talk to your doctor before starting, stopping or changing any medicine. New or worsening speech trouble, facial drooping or sudden weakness can be an emergency. Seek urgent medical help immediately. Full disclaimer
Before the most recent change, my father's Parkinson's schedule (as of 19 October 2026) looked like this:
- 8:00 AM — Oridopa 25/100 two tablets + Madopar HBS 125 one
- 12:00 PM — Oridopa 25/100 two tablets + Madopar HBS 125 one
- 4:00 PM — Oridopa 25/100 two tablets
- 8:00 PM — Oridopa 25/100 two tablets
- 11–11:30 PM — Oridopa 25/100 two tablets + Madopar HBS 125 one
Sometimes, when the medicine seemed ineffective, he took an extra half or one Madopar Dispersible 125, with no fixed timing.
When relief came
Our family's observations of when relief usually came after each dose:
- After 8 AM: roughly 9–11 AM
- After noon: roughly 1 PM to 3:30–4 PM
- After 4 PM: often ineffective
- After 8 PM: roughly 9–11:30 PM
- After the late dose: roughly 12:30–1 AM
Dose failures
Many doses did not bring the relief we expected. Waiting to see whether a dose would help, then seeing no change, was wearing us down.
Total scheduled levodopa
Counting only the scheduled doses, this regimen added up to about 1,300 mg of levodopa per day (ten Oridopa tablets at 100 mg levodopa each, plus three Madopar HBS at 100 mg levodopa each). The "125" on Madopar labels includes the benserazide component, which is why it is not 125 mg of levodopa. Occasional extra dispersible tablets are not included in that figure.