Skip to content
Beyond Parkinson's

What we've noticed at home · not live medical data

My Father's Current Parkinson's Condition
How he is doing now.

My father started a new Parkinson's medicine schedule on 20 October 2026. He seemed to move better at first. But he stayed awake for much of the first night, had a difficult morning and had speech changes we are discussing with his neurologist.

Last family-reported update: 21 October 2026

What we have noticed

Symptoms we've noticed.

These are things we have noticed as a family, not verified clinical findings. We do not know whether each symptom comes from Parkinson's, a medicine or something else.

Long-term challenges

  • His movement varies between ON and OFF periods. At times he is very stiff and cannot stand or walk without help.
  • He feels tightening or pulling in his back, arms and legs.
  • Numbness and tingling.
  • Frequent nighttime urination and constipation.
  • Blood pressure that fluctuates between low and high readings, with dizziness.

Latest observations · 20–21 October 2026

  • He stayed awake for a long time overnight after the 20 October medicine change.
  • On 21 October, we recall ON until about 2 AM, mixed ON and OFF from 2 to 4 AM, and OFF from 4 to 9 AM when he needed help. Later, he was ON from 9 to 11 AM, OFF until noon, then ON until 3 PM. After 3 PM is unknown. These are approximate family recollections, not continuous monitoring.
  • His speech was unclear at times and seemed worse during the night. We also noticed chewing-like mouth movements. The cause is unknown and needs clinical evaluation.

Urgent: New or worsening speech difficulty, facial drooping or sudden weakness can be a medical emergency — seek urgent medical help immediately.

Things he uses for comfort.

Symptom relief at home — family-reported. This section is separate from his Parkinson's prescription.

Axe Brand Universal Oil — the carton and small glass bottle on a white background
A topical comfort product, not a Parkinson's medicine.

External use only

Axe Brand Universal Oil

My father sometimes uses Axe Brand Universal Oil on his hands and legs when they feel numb or tingly. Some days he applies it three or four times, and other days he doesn't use it at all. He feels it helps him, although we don't know whether it changes the underlying problem.

This is a comfort product he rubs on his skin, not a Parkinson's medicine. It is not part of his prescription and we make no claims about any effect on the disease.

My father's Parkinson's medicines now.

Current Parkinson's medicines only, family-reported as of 21 October 2026. The "125" on Madopar labels includes benserazide — it is not 125 mg of levodopa. The exact clock time of the fifth daily dose is not yet verified.

Oridopa 25/100 packaging, family photograph

Current · Tablet

Oridopa 25/100

Carbidopa 25 mg + levodopa 100 mg

2 tablets, 5 times daily. My father continues taking this alongside Madopar Dispersible.

Madopar Dispersible 125 packaging, family photograph

Current · Dispersible tablet

Madopar Dispersible 125

Levodopa 100 mg + benserazide 25 mg

1 tablet, 5 times daily. Every ~4 hours. Exact fifth dose time unverified. Previously an occasional ½–1 tablet, without fixed timing.

Madopar HBS 125 is a former medicine, replaced on 20 October 2026 — it belongs to the treatment history, not the current list. See the full medicine history

Latest treatment change

20 October 2026

Dr. Shivam Om Mittal

Cleveland Clinic Abu Dhabi

What we noticed after the change.

Madopar HBS 125 was replaced with Madopar Dispersible 125, one tablet five times daily (approximately every four hours), while Oridopa 25/100 continued at two tablets five times daily. A family-reported return visit to the neurologist who first saw my father in 2024.

We noticed some better movement early on. He also stayed awake for a long time, had a morning OFF period and had unclear speech at times. We do not know what caused these changes. We are discussing all of them with his doctor.

Read about the treatment change

Personal experience, not medical advice. I share our family's experience here. Talk to your doctor before starting, stopping or changing any medicine. New or worsening speech trouble, facial drooping or sudden weakness can be an emergency. Seek urgent medical help immediately. Full disclaimer